祛瘀宁痛贴抗炎镇痛作用的实验研究  

Experimental study on anti-inflammation and analgesic effects of Quyuningtong paster

作　　者：张乐之[1] 孟德胜[2] 温宝书[1] 吕金胜[2] 魏斌[1] 

机构地区：[1]第三军医大学药理学教研室,重庆400038 [2]第三军医大学附属大坪医院药剂科,重庆400042

出　　处：《中医药学刊》2004年第5期919-921,共3页Study Journal of Traditional Chinese Medicine

摘　　要：Objective: To investigate the anti-inflammation and analgesic effects of Quyuningtong paster (QYNTP). Method : Animal models of acute and subacute inflammations including ear edema caused by xylene , capillary permeability increase by acetic acid in mice and plantar edema by albumen, granuloma by cotton ball in rats were made to observe the anti-inflammation effects of QYNTP . Animal models of pain including reaction of body torsion caused by acetic acid and irritations by heat plate in mice were adopted to study the analgesic action of QYNTP. Result: QYNTP could not only significantly inhibit the ear edema, depress the increase of capillary permeability in mice, but relieve the plantar edema and inhibit the granuloma in rats. In addition, it also remarkably reduce the frequency of body torsion reaction,prolong the latent period of the pain reactions and raise the pain threshold in mice. Conclusion : QYNTP has obvious anti-inflammation and analgesic effects.Objective: To investigate the anti-inflammation and analgesic effects of Quyuningtong paster (QYNTP). Method : Animal models of acute and subacute inflammations including ear edema caused by xylene , capillary permeability increase by acetic acid in mice and plantar edema by albumen, granuloma by cotton ball in rats were made to observe the anti-inflammation effects of QYNTP . Animal models of pain including reaction of body torsion caused by acetic acid and irritations by heat plate in mice were adopted to study the analgesic action of QYNTP. Result: QYNTP could not only significantly inhibit the ear edema, depress the increase of capillary permeability in mice, but relieve the plantar edema and inhibit the granuloma in rats. In addition, it also remarkably reduce the frequency of body torsion reaction,prolong the latent period of the pain reactions and raise the pain threshold in mice. Conclusion : QYNTP has obvious anti-inflammation and analgesic effects.

关 键 词：祛瘀宁痛贴 抗炎 镇痛 中医药理论 中药外治制剂 药理学 

分 类 号：R285.5[医药卫生—中药学]