36例SARS患者外周血象检查结果分析  

Results of determination of peripheral blood in 36 SARS cases.

作　　者：李仲笑[1] 郑辉[1] 谢志威[1] 

机构地区：[1]江门市中心医院检验科,广东江门529071

出　　处：《中国热带医学》2004年第3期382-383,共2页China Tropical Medicine

摘　　要：目的　通过对 3 6例严重急性呼吸综合征 (SARS)患者外周血细胞数据的研究 ,动态监测SARS患者的血象变化 ,探讨血象在发生、发展转归中的临床意义。　方法　收集江门市医院 3 6例确诊SARS患者的外周血检查数据 ,进行动态分析。　结果　入院时 3 6例患者外周血白细胞计数 (WBC)均值为 ( 5 2± 3 0 )× 10 9/L随后WBC升高 ,至第4周有 91 6%病例WBC计数恢复正常 ,入院时淋巴细胞值低于 1 5× 10 9/L者占 88 9% ( 3 2 / 3 6) ,均值为 ( 1 0± 0 5 )×10 9/L ,入院 4周后有 86 1%患者淋巴细胞绝对数恢复正常。 1例血小板降低 ,占 2 8%。其他细胞分类及血红蛋白无明显异常。　结论　白细胞降低或正常及淋巴细胞降低可作为SARS的早期诊断指标 ,淋巴细胞降低可作为SARS早期诊断的标准之一 ;淋巴细胞的降低显示SARS病毒严重侵犯患者免疫功能 。Objective To analyze the hematological characteristic of severe acute respiratory syndrome (SARS) cases and to explore its clinical significance in the occurrence and outcome. Methods Blood samples were collected from 36 SARS cases and hematologically detected by using automatic hematological analyzer on the first day and at least once on the following three days after collection.Dynamic changes were observed at the early,middle and late stages of the disease. Results WBC count increased in 5.6% (2/36) and normal in 44.4% (16/36) of them at early stage,and it was lower than 4.0×10 9/L in 50% (18/36) of the patients [average:(5.2±3.0)×10 9/L]. The lymphocyte was lower than 1.5×10 9/L in 88.9% (32/36) of the cases and normal in 11.1% (4/36) of them [average:(1.0±0.5)×10 9/L]. The platelet was lower than normal in 2.8% (1/36) of the cases and hemoglobin was normal in all patients. Conclusion A normal or lower WBC count is the index for early diagnosis of SARS,while the increase of lymphocytes is obviously another index for monitoring the immune function in the patients.

关 键 词：SARS 外周血象检查 严重急性呼吸综合征 白细胞计数 传染性非典型肺炎 

分 类 号：R563.1[医药卫生—呼吸系统]