异丙基肾上腺素致大鼠心肌损伤的病理形态学研究  

Pathological Morphological Study of Myocardial Lesion Produced by Isoproterenol in the Rat

作　　者：崔松山 王柏苓[1] 黄琪[1] 崔华子[1] 班翔[1] 李树祥[1] 张殿清[2] 关承华[2] 薛玉洁 

机构地区：[1]哈尔滨医科大学病理学教研室 [2]哈尔滨医科大学克山病研究所 [3]哈尔滨制药厂职工医院

出　　处：《哈尔滨医科大学学报》1992年第5期335-337,F004,共4页Journal of Harbin Medical University

基　　金：国家自然科学基金

摘　　要：本实验对异丙基肾上腺素所致大鼠心肌坏死进行了动态病理形态学观察,并应有“多功能图象处理系统”对心肌坏死面积进行定量测量。结果提示了复制大鼠心肌坏死模型的最佳时间以及异丙基肾上腺素对肝、肾组织的影响。In the experiment. the necrosis of rat cardiac muscle resulted from isoproterenol was dynamically observed in the pathological morphology. Furthermore, a 'multi-function-image-treatment-system' was applied to measure the necrosis areas of cardiac muscle quantitatively. The result suggested the optimum time for the animal model reproduction of cardiac muscle necrosis with injection of isoproterenol in rat and thee influence of isoproterenol on the tissues of the liver and the kid(?)ey.

关 键 词：异丙肾上腺素 ISO 心肌梗塞 

分 类 号：R542.202[医药卫生—心血管疾病]