转铁蛋白生理功能及其动态模型  

The Physiological Functions and the Dynamic Model of Transferrins

作　　者：龙华 郑英[2] 

机构地区：[1]中国水产科学研究院长江水产研究所农业部淡水鱼类种质资源与生物技术重点开放实验室 [2]荆州市第一人民医院,湖北荆州434000

出　　处：《湖北农学院学报》2004年第1期30-35,共6页Journal of Hubei Agricultural College

基　　金：农业部"948"资助项目(983094)

摘　　要：综述了转铁蛋白生理功能的全能性、网络性、生理功能的扩展以及最新研究进展;从生理功能角度阐述了转铁蛋白的"V"型三维结构,对糖基、铁离子以及受体结合位点进行了分析;根据文献和转铁蛋白三维结构分析,进而提出了转铁蛋白的四维动态模型,对转铁蛋白与铁离子和转铁蛋白受体的结合过程进行了分析。A brief summary about the all-functional property,the network property, the expansion of transferrin physiological functions,and the newest research progress were done.The three-dimensional structure with 'V' type was discussed from the angle of physiological function.The banding sites of saccharine groups,ferric ions and receptors were also analyzed. Furthermore,four-dimensional dynamic model was brought forward based on reference and transferrin three-dimensional structure analysis.The banding process between transferrins and ferric ions and/or receptors was analyzed.

关 键 词：转铁蛋白 生理功能 “V”型三维结构 糖基 铁离子 受体结合位点 四维动态模型 

分 类 号：Q512.2[生物学—生物化学]