良性前列腺增生症急性尿潴留的临床预测  

The clinical prediction of the acute urinary retention in benignprostatic hyperplasia

作　　者：卢慕峻[1] 姚德鸿[1] 蒋跃庆[1] 董国勤[1] 蔡志康[1] 陆林国[2] 徐秋华[2] 蒋卓[2] 王柏松[3] 

机构地区：[1]上海第二医科大学附属第九人民医院泌尿外科,上海200011 [2]上海第二医科大学附属第九人民医院超声波科,上海200011 [3]上海第二医科大学基础医学院统计学教研室

出　　处：《中国男科学杂志》2004年第3期17-20,23,共5页Chinese Journal of Andrology

摘　　要：目的 应用临床常用指标,预测良性前列腺增生(BPH)发生急性尿潴留(AUR)的几率。方法回顾78名BPH患者病史,分为曾发生AUR(A组)28例,从未发生AUR(B组)50例。分别比较两组间在前列腺总体积(PV)、前列腺移行区体积(TZV)、移行区指数(TZI)和前列腺特异抗原(PSA)、游离前列腺特异抗原(F-PSA)、游离与总前列腺特异抗原比值(F/T-PSA)等指标上的差异性,寻找其中能用于预测AUR的临床指标。应用ROC曲线即受试者工作特性曲线,确定相关指标预测AUR的分界值。结果 A组平均PV、TZV和PSA值皆明显高于B组,上述3个指标在A、B两组间存在显著性差异。而A、B两组在年龄、TZI、F-PSA、F/T-PSA上都无显著性差异。在预测AUR方面PSA可能比前列腺体积指标更具临床价值。结论可通过PV、TZV及PSA来预测BPH中AUR的发生。根据不同临床需要确定预测AUR的临界值,有利于及早对BPH高危人群进行监控和治疗干预。Objective To predict the incidence of acute urinary retention (AUR) in the patients with BPH byclinical measures. Methods According to the occurrences of AUR, 78 BPH patients were divided into 2 groups.Group A included 28 patients who had surffered AUR at least one time, while Group B, the remaining 50 had neverunderwent AUR. The indexes of total prostate volume (PV), the transitional zone volume of prostate (TZV), the indexof transitional zone (TZI), PSA, F-PSA and F/T-PSA between two groups were compared. ROC curve was used todetermine the cut point for predicting AUR in clinical practice. Results The average values of PV, TZV and PSA inGroup A were significantly higher than the counterparts of Group B in terms of the definition of statistics. There wereno statistical differences in other indexes between 2 groups. From our research, PSA maybe had higher clinical signifi-cance than prostate volume to forecast AUR. Conclusion The accidents of AUR in BPH may be predicted by PV,TZV and PSA. We can also distinguish the high-risk populations in early stage for supervision and intervention by theabove clinical cut values.

关 键 词：良性前列腺增生 急性尿潴留 前列腺体积 移行区体积 前列腺特片抗原 

分 类 号：R697.32[医药卫生—泌尿科学] R694.55[医药卫生—外科学]