肝细胞产生胶原纤维的进一步研究  

Further Studies of Collagen Biosynthesis by Hepatocytes

作　　者：赵德育[1] 谢贤春 杨昭徐[3] 李成合[1] 王雅芳 潘延[1] 崔勤[1] 

机构地区：[1]中国医学科学院药物研究所 [2]北京市第二传染病医院 [3]北京市天坛医院

出　　处：《中国医学科学院学报》1992年第5期324-327,T021,共5页Acta Academiae Medicinae Sinicae

摘　　要：对32例肝胆系统疾病的肝穿刺材料进行电镜观察,发现肝内增生的胶原纤维不仅存在于汇管区及Disse腔,也见于肝细胞内。肝细胞内的胶原绝大部分为胶原原纤维,其排列紊乱,混杂于肝细胞器之间,无界膜包裹,提示肝细胞内的胶原原纤维由肝细胞所产生。Electron microscopic observation, was carried out on 32 biopsies from liver and biliary system diseases. It was found that proliferative collagen in the liver was located not only in the portal space and Disse space, but also in the hepatocytes. Most of the collagen seen in hepatocytes were in the form of collagen fibrils, oriented irregularly, intermingled with the organelles and without a delimiting membrane. Therefore, the authors suggest that these collagen fibrils were produced by the hepatocytes themselves.

关 键 词：电子显微镜 肝细胞 胶原 

分 类 号：R333.4[医药卫生—人体生理学]