相转移催化法合成4-甲基伞形酮衍生物的研究  

Synthesis of Derivatives of 4-Methyl Umbelliferone by Phase Transfer Catalysis

作　　者：照那斯图 马英[1] 沃联群[1] 胡运昌[1] 吴卫平[2] 周灯学[2] 朱兰芬[2] 

机构地区：[1]浙江医药高等专科学校,浙江宁波315100 [2]上海市卫生局卫生监督所,上海200031

出　　处：《化学世界》2004年第6期316-319,共4页Chemical World

摘　　要：报道了用乙腈为溶剂,利用聚乙二醇-400为相转移催化剂合成了三种4-甲基伞形酮衍生物b、c、d,考察了诸因素对产率的影响,找出了最佳的反应条件。最佳的反应温度为65～70°C。产物b、c、d的产率分别为:91.1%,78.2%,62.3%。The 4-methylumbelliferone derivatives b,c and d were synthesied by using CH_3CN as solvent and PEG-400 as phase transfer catalyst. The optimum reaction temperature was 65～(70°C). The yields of compound, b,c and d were 91.1%,78.2% and 62.3%, respectively.

关 键 词：4-甲基伞形酮 间苯二酚 乙酰乙酸乙酯 合成 

分 类 号：TQ244.2[化学工程—有机化工]