结核病耐药监测研究报告初步评价  

The evaluation on four reports of tuberculosis drug resistance surveillance

作　　者：邓云峰[1] 孙淑丽[1] 于春宝[1] 王燕[1] 

机构地区：[1]山东省结核病防治中心,济南250013

出　　处：《中国防痨杂志》2004年第2期101-103,共3页Chinese Journal of Antituberculosis

摘　　要：目的　对河南、山东、浙江和广东 4省开展的结核病耐药监测工作的标准化和可比性进行初步评价。方法　按照WHO IUATLD全球耐药监测指南中的有关标准 ,对 4省公开发表的研究报告的有关内容逐项分析。结果　 4省的研究在样本量估算、实验室技术指标、耐药的定义以及耐药的研究对象等方面存在较明显的差异。结论　 4省的结核病耐药监测没有做到统一标准和统一方法 ,不利于比较和考评 ,实际意义下降。尽快建立地区性或全国性统一抽样、选例。Objective To evaluate and compare 4 reports of t u berculosis drug resistance surveillance of He'nan,Shandong,Zhejiang and Guangdon g province.Methods According to the guidelin es of WHO/IUATLD drug resistance surveillance of tuberculosis project, the items of every report was checked and analyzed.Results There were di fference on estimation of sample size,technique indexes which be used in laborat ories, the definitions of primary and acquired drug resistance among fo ur reports.Conclusion Only the standardization of methods be us ed,the results will be comparable among participating laboratories. It is impor tant to establish surveillance of drug resistance system in nationwide.

关 键 词：结核病 耐药性 监测 药物治疗 

分 类 号：R52[医药卫生—内科学]