栾树皮化学成分的研究  

Study on the chemical constitutents from the barks of Koelreuteria paniculata

作　　者：雷海民[1] 龚卫红[1] 毕葳[1] 张静[1] 林文翰[2] 

机构地区：[1]北京中医药大学中药学院,北京100102 [2]北京大学天然药物及仿生药物国家重点实验室,北京100083

出　　处：《中国药学杂志》2004年第4期253-254,共2页Chinese Pharmaceutical Journal

基　　金：国家自然科学基金重点课题资助项目(29732040)

摘　　要：目的 对北京产栾树(Koelreuteria paniculata Laxm.)皮的化学成分进行研究。方法 利用溶剂提取、硅胶色谱柱和Sepha-dex LH-20进行分离,根据化合物的理化性质和光谱数据鉴定其结构。结果 分离鉴定了3个皂苷类化合物,分别为3β-羟基-羽扇豆烷(Ⅰ)、3β,28-二羟基-羽扇豆烷(Ⅱ)、3β-羟基-28-羽扇豆酸(Ⅲ)。结论 化合物Ⅰ,Ⅱ,Ⅲ为首次从该植物中发现。OBJECTIVE To investigate the chemical constituents of the barks of Koelreuteria paniculata Laxm. METHODS Components were separated by means of solvent extraction and chromatography on silical and sephadexLH-20. The structures were determined by spectral analysis and chemical properties. RESULTS Three compounds were obtained and elucidated as 3β-hydroxyl-lupinane, 3β, 28-di-hydroxyl-lupinane and 3β-hydroxyl-28-lupinic acid. CONCLUSION These compounds were obtained from the plant for the first time.

关 键 词：栾树 化学成分 皂苷类化合物 分离 鉴定 

分 类 号：R284[医药卫生—中药学]