碘和甲状腺肿流行规律的发现、检验和建立  

Findings, confirming and establishment of epidemic law between iodine and goiter rate

作　　者：于志恒[1] 刘守军[2] 朱惠民[1] 王世英 时钟孚[4] 杨英奎[5] 苏晓辉[2] 

机构地区：[1]河北医科大学地方病研究室,石家庄050017 [2]哈尔滨医科大学中国疾病预防控制中心地方病控制中心 [3]河北省地方病防治所 [4]贵阳医学院 [5]山东省地方病防治研究所

出　　处：《中国地方病学杂志》2004年第3期195-197,共3页Chinese Jouranl of Endemiology

摘　　要：为建立碘和甲状腺肿流行呈U形曲线关系的规律,调查了河北、山东、贵州3省17个点的水碘、尿碘和甲状腺肿大率,并用国际通用的PPS抽样法和国家统一的盐碘、尿碘、甲状腺容积的标准检测方法,由省级单位加以实施。发现随着水碘、尿碘的递增,甲肿率呈现由高而低再低而高的U形趋势,这种趋势得到了1999、2002两次全国碘缺乏病监测数据和必需微量元素的剂量效应曲线的验证。碘与甲状腺肿流行呈U形关系是一个客观存在的规律。To find, confirm and establish the epidemic law of U-shape relation between iodine and goiter rate, water iodine, urinary iodine and goiter prevalence were investigated in 17 sites in Hebei, Shandong and Guizhou in finding 'law'. In confirming the law, 'probability proportionate to size' sampling method, the international current one, and standardized measuring methods of salt iodine, urinary iodine and thyroid volume, the uniform national ones, were used and put in action by provincial units. With the increase of water iodine and urinary iodine, goiter prevalence shows U-shape trend from the high to the low and then from the low to the high. This trend is confirmed by the surveillance data of national iodine deficiency disorders in 1999 and 2002. The epidemic law that iodine and goiter rate show U-shape relation has been established.

关 键 词：甲状腺肿 流行规律 U形曲线 水碘 尿碘 

分 类 号：R581.3[医药卫生—内分泌]