106例老年人不稳定型心绞痛各时段血浆肾上腺素水平变化  

The levels of noradrenaline and adrenaline in each phase in 106 elderly patients with unstable angina

作　　者：刘丰[1] 黄卫民[1] 陈蕴贤[1] 

机构地区：[1]广东省广州市第一人民医院,510180

出　　处：《中国全科医学》2004年第9期616-617,共2页Chinese General Practice

基　　金：广州市科委"九五"科技攻关重点项目资助 [编号 :99- 2 - 1 0 2 - 0 6]

摘　　要：目的　为探讨老年人不稳定型心绞痛急性发作期间及稳定期的血浆去甲肾上腺素 (NE)及肾上腺素水平 (E)。方法　 10 6例老年UAP患者分别于发作即时、发作后 2 4h及稳定后 2周测定血浆NE、E的含量 ,并设对照组比较。结果　 3个时段的NE含量分别为 (5 4 6 90± 12 3 70 ) μg/ml、 (5 16 6 0± 98 80 ) μg/ml,(38 5 4± 12 85 ) μg/ml;E含量分别为 :(92 2 70± 4 12 6 9) μg/ml,(913 2 7± 4 4 1 6 0 ) μg/ml,(10 0 2 0± 2 8 5 0 ) μg/ml。其 2 4小时内的NE、E含量与平稳后 2周的含量间差别有显著性意义 (P <0 0 1)。对UAP的初发型及劳力恶化型分别对照 ,均有差异。为排除药物对其的影响 ,分别以 β -受体阻滞剂、Ca2 + 拮抗剂等对照 ,差异仍有显著性意义。结论　老年人在UAP的急性期中交感神经张力增高 ,NE。ObjectiveTo observe the levels of NE and E in elderly unstable angina in acute phase and stable phase.Methods106 UAP patients were studied.The NE and E were measured in three times (in acute happen,24 hours,Two weeks after stable).ResultsThe NE were 546.90±123.7μg/ml,516.60±98.8μg/ml,38.54±12.85μg/ml;and the E were 922.7±412.69μg/ml,913.27±441.6μg/ml,100.20±28.5μg/ml.The levels of NE and E in 24 hours were higher.There was a significant difference in comparison.With after stable (P<0.01).80 while primary and accelerated angina and exude the influence of β-blocker and Ca 2+ channel blocker,the significant difference was same.ConclusionThe levels of NE and E was raised and sympathetic nervous tension in acute phase in elderly patients of unstable angina.

关 键 词：老年人 不稳定型心绞痛 血浆肾上腺素 去甲肾上昧素 

分 类 号：R541.4[医药卫生—心血管疾病]