复方磺胺甲卟恶唑不良反应267例分析  

An Analysis of Adverse Reactions Induced by Compound Sulfamethoxazole Tablets in 267 Cases

作　　者：伦新强[1] 

机构地区：[1]广西柳州医学高等专科学校第一附属医院,广西柳州545002

出　　处：《药物流行病学杂志》2004年第3期139-140,153,共3页Chinese Journal of Pharmacoepidemiology

摘　　要：目的 :汇集复方磺胺甲卟恶唑片的不良反应 ,为临床合理用药提供参考。方法 :对 1975～ 2 0 0 2年国内报道的 2 6 7例不良反应进行分析和综合。结果 :2 6 7例涉及的临床类型主要有变态反应 12 1例 (45 .32 % ) ,消化系统反应 6 9例 (2 5 .84 % ) ,神经系统反应 2 7例 (10 .11% ) ,泌尿系统反应 2 1例 (7.87% ) ,血液系统反应 2 0例(7.4 9% ) ,心血管系统反应 5例 (1.87% ) ,内分泌紊乱 4例 (1.5 0 % )。结论 :合理用药 ,注意防治不良反应。Objective: To investigate the characteristics of emergence of ADR induced by SMZ-TMP tablet and to provide some guidance for clinical medicine and rational drug use.Method: 267 cases with ADR induced by SMZ-TMP tablets reported in domestic literatures issued from 1975～2002 were collected and statistically analyzed.Result: 267 cases with various clinical ADR manifestations were analyzed, such as allergic reaction(121), digestive system(69), nervous system(27), urinary system(21), blood system(20), cardiovascular system (5),endocrine disorder(4).Conclusion: SMZ-TMP tablet should be rationally used,we should pay attention to the prevention and cure of ADR.

关 键 词：复方磺胺甲e唑 不良反应 合理用药 消化系统反应 

分 类 号：R978.21[医药卫生—药品]