以社区为基础的静脉吸毒人群丙型肝炎病毒感染危险因素研究  

Community-based survey of HCV transmission risk factors among injection drug users

作　　者：刘石柱[1] 陈康林[2] 朱国平[2] 巫俊林 冯成玉[2] 范建英[2] 秦光明[3] 孙乔[3] 刘刚[3] 郑国英[3] 何益新[1] 周枫[1] 阮玉华[1] 邵一鸣 

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心 [2]西昌市皮肤病性病防治站,四川西昌615000 [3]四川省疾病预防控制中心,四川成都610031

出　　处：《疾病控制杂志》2004年第1期19-21,共3页Chinese Journal of Disease Control and Prevention

基　　金：国家十五科技攻关项目 (2 0 0 1BA70 5 B0 2 )资助

摘　　要：目的　了解四川省凉山州地区静脉吸毒人群丙型肝炎病毒感染情况及其危险因素。方法　以社区为基础调查静脉吸毒人群丙型肝炎病毒感染危险因素 ,通过检测研究对象的丙型肝炎病毒抗体确定是否感染丙型肝炎病毒。结果　静脉吸毒人群丙型肝炎病毒感染率为 71.0 % (2 6 9/379)。在多因素 logistic回归模型分析中 (P<0 .0 5 ) ,共用注射器具次数的 OR值为 2 .0 5 3,其 95 %CI为 1.4 5 8～ 2 .891。在单因素χ2 分析中 (P <0 .0 5 ) ,共用注射器具次数、共用注射器具吸毒年限、近 3个月平均每天静脉吸毒频率等多个因素同丙型肝炎病毒感染有关。Objective To study risk factors of HCV transmission among injection drug users (IDUs) in Liangshan, Sichuan province. Methods A community-based survey was conducted to investigate high risk behavior factors of HCV transmission and to test HCV antibody among IDUs. Results The HCV prevalence was 71.0% (269/379) among IDUs. Using a multivariate logistic regression model (P<0.05), the OR of sharing times of injection equipment in the past was 2.053,and 95% CI was 1.458～2.891. In univariate analysis, sharing times of injection equipment, sharing years of injection equipment, frequency of daily injection in the last three months, and sharing of needles, water, and vessels in the last three months were statistically significant risk factors of HCV transmission. Conclusions HCV infection risk factors such as sharing patterns of injection equipment should be investigated in the future.

关 键 词：社区 静脉吸毒 丙型肝炎病毒感染 危险因素 病因学 

分 类 号：R512.63[医药卫生—内科学]