系列手性二齿配体在硫醚的不对称氧化反应中的应用  

Application of a Series of Chiral Bidentate Ligands in Asymmetric Oxidation of Sulfide

作　　者：彭云贵[1] 冯小明[2] 崔欣[3] 蒋耀忠[3] 

机构地区：[1]西南师范大学化学化工学院,重庆400715 [2]四川大学化学学院四川省绿色化学与技术重点实验室,成都610064 [3]中国科学院成都有机化学研究所不对称合成联合开放实验室,成都610041

出　　处：《有机化学》2004年第5期558-562,共5页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金 (No.2 9832 0 2 0 )资助项目

摘　　要：设计合成了系列手性二齿配体 ,并将它们与Ti(OPr i) 4 生成的配合物用于催化硫醚的不对称氧化 ,考察了配体的结构对反应活性和对映选择性的影响 。A series of chiral bidentate ligands were designed and synthesized, and their complexes, which derived from coordinating with Ti (OPr-i)(4), were employed in the catalytic asymmetric oxidation of sulfide. Both the influence of the structure of the chiral ligands to the reactivity and enantioselectivity and the relationship of the configurations between the chiral ligands and the products were investigated.

关 键 词：手性二齿配体 硫醚 不对称氧化反应 反应活性 对映选择性 亚砜 

分 类 号：O621.25[理学—有机化学]