MATS对高胆固醇血症大鼠血脂的影响  

Effect of MATS on blood-Iipids in hypercholesteremic rats

作　　者：陈滴[1] 马秀俐[1] 赵然[1] 曲绍春[2] 

机构地区：[1]白求恩医科大学药物研究室 [2]白求恩医科大学药理教研室

出　　处：《白求恩医科大学学报》1993年第6期539-541,共3页Journal of Norman Bethune University of Medical Science

摘　　要：本文探讨了甲基烯丙基三硫(MATS)对实验性高胆固醇血症大鼠脂质代谢紊乱的影响。实验结果表明:MATS具有明显降低高胆固醇血症大鼠血清中TC、TG、LDL及升高HDL作用,其作用随服用剂量增加有增强趋势。同时与降血脂药吉非罗奇Gimfibrozil(125mg/kg·日)比较,当 MATS口服剂量达到15mg/kg·日时二者血清中 TC、LLDL无显著差异,但对降低血清TG及升高 HDL明显优于吉非罗奇。The effect of MATS on blood-lipids in experimental hypercholesteremic rats was observed. MATS exerted the effect of decreasing significantly serum TC, LDL. TG, and increasing serum HDL. The dosage of MATS is directly related to it's effect on the blood lipids. The effect of MATS at a dosage of 15 mg/kg · d is stronger than that of Gimfibrozil (125mg/kg · d) in decreasing serum TG and increasing serum HDL.

关 键 词：薤白 高胆固醇血症 血脂 

分 类 号：R282.710.5[医药卫生—中药学]