N′-四氮唑基-N-取代苯氧乙酰基硫脲的合成及生物活性  

Synthesis and Biological Activity of N′-Tetrazolyl-N-substitutedphenoxy Acetyl Thiourea

作　　者：李淑贤[1] 

机构地区：[1]邯郸师范专科学校化学系,河北邯郸056005

出　　处：《河北大学学报（自然科学版）》2004年第3期281-283,共3页Journal of Hebei University(Natural Science Edition)

摘　　要：通过4-氯苯氧乙酸、2,4-二氯苯氧乙酸与硫氰酸钾反应合成取代苯氧异硫氰酸酯,再分别与5-氨基-1,2,3,4-四氮唑发生亲核加成反应,合成了2种未见报道的酰基硫脲衍生物.其结构经元素分析、IR和1HNMR确证,并初步测定了其生物活性.Two new compounds, N′-tetrazolyl-N-substitutedphenoxy acetyl thiourea were synthesized by addition reaction of substitutedphenoxy acetylisothiocyanates with 5-amino-1,2,3,4-tetrazole. Their physical properties, IR, ()~1H NMR and elementary analysis were characterized, biological activity tests were originally studied too.

关 键 词：5-氨基-1 2 3 4-四氮唑 取代苯氧乙酰基硫脲 生物活性 

分 类 号：O621.3[理学—有机化学]