用钐和四氯化钛体系一锅法合成咪唑烷衍生物  

One Pot Synthesis of Imidazolidine Derivatives by Sm/TiCl_4

作　　者：余明新[1] 张永敏[1] 

机构地区：[1]浙江大学化学系,杭州310027

出　　处：《有机化学》2004年第6期683-685,共3页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金 (No.2 9872 0 1 0 )资助项目

摘　　要：在四氢呋喃溶液中 ,用Sm/TiCl4体系还原亚胺合成了咪唑烷衍生物 .发现当没有促进剂 1,2 二溴乙烷时 ,咪唑烷衍生物的产率小于 2 0 %,加入 1,2 二溴乙烷后 ,产率大大提高 .产物的结构通过IR ,1 HNMR和MS光谱确证 .Certain imines lead to the formation of imidazolidine derivative in THF with Sni/TiCl4 system. It was found that products of reductive coupling could be obtained in below 20% yields without 1,2-dibromoethane, while products of reductive coupling in moderate yields when I 2-dibromoethane was added. The structures of all products were confirmed by IR, H-1 NMR and MS spectra. According to the results of the experiment, a possible mechanism was proposed.

关 键 词：咪唑烷衍生物 钐 四氯化钛 一锅法 合成 亚胺 四氢呋喃 

分 类 号：O626[理学—有机化学]