速眠新在大鼠麻醉中的应用分析  

Experience in Anesthetizing Rats with SU-MIAN-XIN

作　　者：孙同柱[1] 付小兵[1] 翁立新[1] 郑曙云[1] 梁雪梅[1] 赵京禹[1] 陈伟[1] 

机构地区：[1]中国人民解放军304医院全军创伤修复重点实验室,北京100037

出　　处：《实验动物科学与管理》2004年第2期48-49,共2页Laboratory Animal Science & Administration

摘　　要：分析不同剂量速眠新麻醉大鼠的效果。将 18只大鼠分成三组 ,分别按每千克体重 0 4、0 8、1 2mL速眠新进行肌肉注射麻醉。结果给予速眠新后分别在 ( 7± 1)、( 5± 1)和 ( 4± 1)min大鼠进入麻醉状态 ,麻醉维持时间分别为 ( 31± 6 )、( 89± 11)和 ( 111± 10 )min。大鼠在麻醉维持期间呼吸频率分别为 ( 6 2± 12 )、( 6 0± 11)和 ( 70± 15 )次 /min ,心跳频率分别为 ( 175± 16 )、( 16 5± 12 )和 ( 16 5± 13)次 /min。速眠新麻醉大鼠的效果满意 ,适宜剂量为每千克体重肌肉注射 0 4mL～ 0 8mL。To observe the effects of different doses of SU-MIAN-XIN in anesthetizing rats. 18 Wistar rats were divided into three groups with 6 rats in each group. Each group was anesthetized with SU MIAN XIN intramuscularly in dosage of 0\^4mL/kg\,0\^8mL/kg\,1\^2mL/kg, respectively. The rats that were given in a dose of 0\^4mL/kg took(7±1)min to get properly anesthetized and could maintain (31±6)min; 0\^8mL/kg were (5±1)min and (89±11)min; 1\^2mL/kg were (4±1)min and (111±10)min. Under the anesthesia, respiratory rates were(62±12)\,(60±11)\,(70±15) per minute and heart rate (175±16)\,(165±12)\,(165±13) per minute, respectively. Rats can be anesthetized with SU-MIAN-XIN with the practical doses from 0\^4mL/kg to 0\^8mL/kg by given intramuscularly.

关 键 词：大鼠 麻醉 速眠新 

分 类 号：R971[医药卫生—药品]