多巴酚丁胺负荷核素心肌显像在冠心病诊断中的应用  

Application of DBA-SPECT in diagnosis of coronary artery disease

作　　者：吴晓君[1] 马晶[2] 刘朝中[1] 

机构地区：[1]空军总医院心内科,北京100036 [2]解放军总医院老年病心血管研究所,北京100851

出　　处：《空军总医院学报》2004年第2期67-69,共3页Journal of General Hospital of Air Force,PLA

摘　　要：目的　药物负荷核素心肌显像在冠心病诊断中的价值。　方法　选取本院胸痛可疑冠心病 ,且能耐受平板运动试验的住院患者 5 5例 ,进行多巴酚丁胺 (DBA)负荷99mTc MIBI门控心肌灌注断层显像 (SPECT) ,平板运动试验检查 ,部分行冠脉造影检查。　结果　DBA SPECT结果 4 0 % (2 2 / 5 5 )的患者DBA负荷SPECT结果呈可逆性放射性稀疏 (即心肌缺血改变 )。 2 0例有冠脉造影对照的患者中 ,DBA负荷SPECT诊断冠心病的灵敏度 87 5 % (7/ 8) ,特异性 75 % (9/ 12 ) ,准确率 80 %(16 / 2 0 )。Objective To investigate the applicative value of DBA stress SPECT in the diagnosis of coronary artery disease. Methods 55 cases who suffered from suspicious CHD due to chest pain were selected. DBA stress SPECT and exercise test were performed,and some subjects underwent coronary angiograph. Results About 40% (22/55) of the subjects showed radioactive rarefaction by DBA stress SPECT,which means cardiac ischemia. Combined with results of angiography,DBA stress SPECT revealed relatively high sensitivity(87.5%),specificity (75%) and accuracy (80%) in diagnosis of coronary coronary disease. Conclusion DBA stress SPECT is a relatively sensitive and specific non-invasive technique for diagnosis of coronary artery disease.

关 键 词：多巴酚丁胺 诊断应用 ^99m锝SESTAMIBI 诊断 冠状动脉疾病 诊断 心肌再灌注 

分 类 号：R543.3[医药卫生—心血管疾病] R814.42[医药卫生—内科学]