Synthesis of RGD-aPEG-lactoside, a Potential Anti-metastasis Glycoconjugate  

作　　者：ShuChunLI LiMinNIU HuiLI,ZhongJunLI QingLI 

机构地区：[1]DepartmentofChemicalBiology,SchoolofPharmaceuticalSciencesandNationalResearchLaboratoryofNaturalandBiomimeticDrugs,PekingUniversity,Beijing100083

出　　处：《Chinese Chemical Letters》2004年第5期532-534,共3页中国化学快报（英文版）

摘　　要：The adhesive interaction between tumor cells and host cells or the extra cellular matrix plays a crucial role in metastasis. Due to the anti-metastasis effects of RGD (arginyl-glycyl -aspartic acid) and some oligosaccharides, RGD-aPEG-Lactoside was prepared which will be used on anti-metastasis.The adhesive interaction between tumor cells and host cells or the extra cellular matrix plays a crucial role in metastasis. Due to the anti-metastasis effects of RGD (arginyl-glycyl -aspartic acid) and some oligosaccharides, RGD-aPEG-Lactoside was prepared which will be used on anti-metastasis.

关 键 词：RGD LACTOSE PEG anti-metastasis. 

分 类 号：Q533.3[生物学—生物化学]