加味四君子汤防治肝癌介入治疗后肝储备功能损伤的临床研究  

Clinical Observation on Prevention of“Jia Wei Si Jun Zi Tang”from Damage of Hepatic Reserving Function after Intervention of Liver Cancer

作　　者：张蓓[1] 黄国贤[1] 张亚奇[1] 陈徐贤[1] 胡丕丽[1] 徐伯平[1] 

机构地区：[1]中山大学附属肿瘤医院,510060

出　　处：《中药材》2004年第5期387-389,共3页Journal of Chinese Medicinal Materials

摘　　要：目的:观察加味四君子汤防治和治疗肝癌介入治疗后肝储备功能损伤的临床疗效。方法:将65例中晚期肝癌患者随机分成两组。对照组(33例)在介入治疗后予西药常规护肝治疗,治疗组(32例)在对照组治疗的基础上加服加味四君子汤。两组分别在第1、第2次介入前和第2次介入后一个月各检查吲哚靛青绿15min储留率(ICGR_(15))。观察两组患者ICGR_(15)治疗前后的变化。结果:第1次介入治疗前ICGR_(15):治疗组11.13％±7.28％,对照组11.81％±7.43％(P>0.05);第2次介入治疗前ICGR_(15):治疗组12.18％±5.22％,对照组18.36％±9.82％(P<0.05);第2次介入治疗后一个月ICGR_(15):治疗组12.83％±5.28％,对照组19.12％±9.96％(P<0.05)。结论:肝癌介入治疗后加用加味四君子汤防治肝储备功能损伤的疗效明显优于单纯西医治疗。Objective: To observe prevention of 'Jia Wei Si Jun Zi Tang' (JWSJZT) from damage of hepatic reserving function after intervention of liver cancer. Methods:65 patients with advance stage of liver cancer were randomly into two groups, the control group (regular protective therapy) and the treatment group (regular protective therapy+JWSJZT). There were 33 and 32 cases in the control group and treatment group, respectively. ICGR_(15) was detected before the first and the second intervention treatment and one month after the second intervention treatment, respectively. ICGR_(15) change was observed before and after the intervention treatment in the two groups. Results:lCGR_(15) was 11.13 %±7.28 % in the treatment group and 11.81%±7.43% in the control group (P>0.05) before the first intervention;18.36%±9.82% in the control group and 12.18%±5.22% in the treatment group, before the second invention treatment(P<0.05);19.12%±9.96% in the control group and 12.83%±5.28% in the treatment group one month after the second intervention treatment (P<0.05). Conclusion: The western medicine+JWSJZT group is superior in curative effect to western medicine group.

关 键 词：四君子汤 防治 肝癌 介入治疗 肝储备功能损伤 临床研究 

分 类 号：R273[医药卫生—中西医结合]