气相催化氧化法烟酸的绿色合成研究  

Study on Green Synthesis of Nicotinic Acid by Gas-phase Catalytic Oxidation

作　　者：黄海凤[1] 朱冰春[2] 卢晗锋[2] 刘华彦[2] 陈银飞[2] 

机构地区：[1]浙江工业大学生物与环境工程学院 [2]浙江工业大学化学与材料工程学院,浙江杭州310014

出　　处：《高校化学工程学报》2004年第3期334-338,共5页Journal of Chemical Engineering of Chinese Universities

基　　金：浙江省自然科学基金项目资助(202083)

摘　　要：以3-甲基吡啶为原料,用V2O5/TiO2系催化剂,采用气相氧化法一步合成烟酸.水与3-甲基吡啶分开进料,通入催化剂床层后混合进行反应.实验考察了V2O5用量、助剂、反应温度、进水量及空速等因素对催化剂活性的影响.当V2O5负载量为25%,反应温度320～340℃,3-甲基吡啶空速0.15-0.8h-1,空气、水、3-甲基吡啶的进料摩尔比为110:100:1时,烟酸的产率达到90%以上.Gas-phase 3-picoline can be directly oxidized by O2 to nicotinic acid in the presence of TiO2 impregnated V2O5 catalyst. During the process water and 3-Picoline are fed separately into the catalyst bed. Factors affecting the activity of the catalyst such as the amount of V2O5, the kinds of promoter, the reacting temperature, the quantity of water, and the space velocity were studied. The results show that the highest yield of nicotinic acid (2O5 content is about 25%(wt), the reaction temperature is 320-340°C, the velocity of 3-Picoline input is 0.15-0.8 h-1, the mole ratio of air/water/3-picoline is 110:100:1.

关 键 词：3-甲基吡啶 烟酸 气相氧化 V2O5/TIO2催化剂 

分 类 号：O643.321[理学—物理化学] TQ203.2[理学—化学]