头孢克肟侧链的合成研究  

Study on Synthesis of Cefixime Side Chain

作　　者：傅雪晶[1] 冯亚青[1] 

机构地区：[1]天津大学化工学院,天津300072

出　　处：《合成化学》2004年第4期348-350,364,J002,共5页Chinese Journal of Synthetic Chemistry

摘　　要：介绍了头孢克肟的抗菌活性。综述了头孢克肟侧链的合成方法 ,提出了从氯乙酰乙酸乙酯为原料经肟化、缩合 2步反应合成头孢克肟侧链是一条适合于工业化生产的工艺路线。参考文献 2The medical properties of Cefixime are introduced. Synthesis of Cefixime side chain several synthetic methods from different raw materials were discussed in detail. A preparation method sutiable for industrial application was also suggested. 20 References were quoted.

关 键 词：头孢克肟 合成 铡链 综述 

分 类 号：O626.25[理学—有机化学]