肺间质纤维化患者血液中基质金属蛋白酶9的变化  

To study change of matrix metalloproteinase-9 in serum of pulmonary fibrosis patients

作　　者：杨伟国[1] 居军[1] 马惠[1] 

机构地区：[1]甘肃省临床检验中心,甘肃兰州730000

出　　处：《检验医学》2004年第3期254-255,共2页Laboratory Medicine

摘　　要：目的　了解基质金属蛋白酶 9(MMP9)与肺间质纤维化的相关程度。方法　用酶联免疫吸附试验(ELISA)检测血清中MMP9的含量。结果　肺间质纤维化组MMP9水平明显高于正常对照组 ,两组比较差异有显著性 (P <0 .0 5 )。结论　MMP9可作为了解肺间质纤维化进程及肺间质纤维化辅助诊断的指标。Objective To investigate the relation between matrix metalloproteinase 9(MMP 9) and pulmonary fibrosis. Methods To determine the concentration of MMP 9 in serum by ELISA. Results MMP 9 contents had significant difference between pulmonary fibrosis group and control group. Conclusions MMP 9 can be looked as an index to diagnose pulmonary fibrosis.

关 键 词：肺间质纤维化 基质金属蛋白酶9 MMP9 酶联免疫吸附试验 ELISA 

分 类 号：R563[医药卫生—呼吸系统]