头针电刺激对心律失常大鼠心肌细胞动作电位的影响  

Effect of Scalp Electroacupuncture on Action Potentials of Ventricular Muscles in Arrhythmia Rats

作　　者：尤行宏[1] 吴丰华[1] 胡平[1] 何承敏[1] 

机构地区：[1]湖北中医学院生理教研室,湖北武汉430061

出　　处：《湖北中医学院学报》2004年第2期15-17,共3页Journal of Hubei College of Traditional Chinese Medicine

基　　金：湖北省卫生厅研究项目资助课题 (WZ0 15 48)

摘　　要：目的 :观察头针电刺激“额旁 1线”区域对氯化钡诱发大鼠心律失常动作电位的影响。方法 :在氯化钡(BaCl2 )所致的实验性心律失常模型上 ,针刺大鼠头部双侧“额旁 1线”区域 ,并给予电针刺激 ,采用浮置式玻璃微电极方法 ,记录实验中各组大鼠的动作电位 ,观察不同时刻单一心肌细胞动作电位的变化。结果 :头针“额旁 1线”对心律失常大鼠心肌电活动具有明显的改善作用 ,头针可有效调整心肌动作电位的改变 ,加快心肌跨膜电位的恢复过程。结论 :头针能有效改善心律失常时的动作电位变化 ,发挥抗实验性心律失常作用 ,说明“额旁 1线”作为头部胸腔区域 ,与心血管的功能活动有着密切关系。To research the effects of scalp electroacupuncture on lateral line 1 of forehead on action potentials of ventricular muscles in experimental arrhythmia rats induced by Barium Chloride. Methods: Barium Chloride-induced ventricular arrhythmia model was induced in wistar rats, electroacupuncture on the both area of lateral line 1 of forehead was then given. Transmembrane action potential was recorded by floating microeletrode in 30 rats in vivo. Results: Scalp electroacupuncture have obvious effect on action potentials of ventricular muscles of the arrhythmia rats. After treatment of scalp electroacupuncture on lateral line 1 of forehead, The change of transmembrane action potentials of the rats was ameliorated by scalp electroacupuncture . Conclusion : Scalp acupuncture have the curative effect of arrhythmia obviously . The area of lateral line 1 of forehead has affinity connection with heart function.

关 键 词：头针 电刺激 心律失常 大鼠 心肌细胞 动作电位 

分 类 号：R259.417[医药卫生—中西医结合] R245.321[医药卫生—中医内科学]