微乳对槲皮素增溶作用的实验研究  

Study on the enhancing effect of microemulsion on solubility of Quercetin

作　　者：马玉坤[1] 冯杨[1] 孔蓓蓓[2] 邹满[3] 

机构地区：[1]济南第二人民医院,济南250000 [2]山东大学药学院,济南250012 [3]山东体育学院图书馆,济南250012

出　　处：《齐鲁药事》2004年第3期46-48,共3页qilu pharmaceutical affairs

摘　　要：目的　研究O/W型微乳对槲皮素的增溶作用。方法　以三角相图法制备了吐温 80 -乙醇 -花生油 -水的微乳体系,用比色法测定了在微乳、水和吐温 80 -乙醇 -水体系中槲皮素的溶解度,并考察了槲皮素O/W型微乳的初步稳定性。结果槲皮素在微乳中的溶解度为水中的 5 0倍以上。结论　所制备的微乳对槲皮素有明显的增溶作用。Objective To study the enhancing effect of O/W microemulsion on the solubility of Quercetin. Methods Microemulsion system containing tween 80-alcohol-peanut oil-water was prepared based on the triangle phasdiagram diagram, and solubility of Quercetin in microemulsion, water and tween 80-alcohol-water was analysed by the way of UV. The stability of microemulsion was preliminarily examined. Results Solubility of Quercetin in microemulsion was 50 times more than that in water. Conclusion The prepared microemulsion had significantly enhancing effect on the solubility of Quercetin.

关 键 词：微乳 三角相图 表面活性剂 槲皮素 

分 类 号：TQ460.6[化学工程—制药化工]