电化学及光电化学传感器检测胱抑素C的研究进展  

Research Progress on Detection of Cystatin C by Electrochemical and Photochemical Sensors

作　　者：夏梦诗 王晓龙[1] 

机构地区：[1]重庆医科大学附属第二医院,重庆

出　　处：《分析化学进展》2021年第4期246-250,共5页Advances in Analytical Chemistry

摘　　要：胱抑素C是一种由有核细胞合成的碱性低分子量蛋白,相比肌酐而言,胱抑素C能够更加敏感地反映肾脏受损情况,尤其在CKDI、II时期。现存的胱抑素C临床检测方法,因价格昂贵、操作复杂、灵敏度低等原因在临床受限。但近几年兴起的电化学、光电化学传感器体系检测胱抑素C,有效地弥补了以往的检测缺陷,且能达到床旁快速检测的目标,本文就电化学、光电化学传感器体系检测胱抑素C的研究进行综述。Cystatin C is an alkaline low-molecular-weight protein synthesized by nucleated cells. Compared with creatinine, cystatin C is more sensitive to renal damage, especially in CKD stages I and II. Existing cystatin C clinical detection methods are limited due to high cost, complex operation and low sensitivity. However, in recent years, the emergence of electrochemical and photoelectric sensor systems to detect cystatin C has effectively made up for the defects of the previous detection, and can achieve the goal of rapid detection near the bed. This paper reviews the research on the detection of cystatin C by electrochemical and photoelectric sensor systems.

关 键 词：胱抑素C 电化学 光电化学 快速检测 

分 类 号：TP2[自动化与计算机技术—检测技术与自动化装置]