三维柔性电化学传感器在细胞信号分子监测中的研究进展  

Research Progress of Three Dimensional Flexible Electrochemical Sensors in Cell Signal Molecular Monitoring

作　　者：朱彩玲 于春梅[1] 霍晓磊 

机构地区：[1]南通大学公共卫生学院,江苏 南通

出　　处：《分析化学进展》2022年第4期327-333,共7页Advances in Analytical Chemistry

摘　　要：生物体通过释放各种信号分子来实现细胞间和细胞外信息传递,进而对机体的整体功能进行调节控制,信号分子在生物体中的异常表达会导致多种疾病,因此监测这些生物信号分子对人类健康研究极具意义。三维柔性电化学传感器具有良好的力学性能、灵敏度和稳定性等特性,可以模仿体内细胞的自然环境,实现三维细胞培养和监测。本文简要介绍了三维柔性电化学传感器在细胞生物信号分子监测中的发展和应用。Organisms transmit intercellular and extracellular information by releasing various signaling molecules, and then regulate and control the overall function of the body. The abnormal expres-sion of signaling molecules in organisms can lead to a variety of diseases, so monitoring these bio-logical signaling molecules is of great significance for human health research.3D flexible electro-chemical sensors have good mechanical properties, sensitivity and stability, which can imitate the natural environment of cells in vivo and realize 3D cell culture. This paper briefly introduces the development and application of 3D flexible electrochemical sensors in Monitoring of Biosignal Molecules.

关 键 词：三维柔性电化学传感器 生物信号分子 电化学检测 细胞培养 

分 类 号：O657.1[理学—分析化学] TP212[理学—化学]