尿酮体的临床意义  

The Clinical Significance of Urine Ketone

作　　者：弋锐田 刘红莉 赵英仁[3] 牛迎花[3] 

机构地区：[1]西安交通大学第一附属医院重症医学科,陕西西安 [2]西安市第八人民医院检验科,陕西西安 [3]西安交通大学第一附属医院感染性疾病科,陕西西安

出　　处：《临床医学进展》2019年第2期151-157,共7页Advances in Clinical Medicine

摘　　要：酮体是人体内脂肪在肝脏代谢的中间产物,参与机体供能,酮体过多又能导致机体酸中毒,引起酸碱平衡紊乱。研究发现酮体与糖尿病酮症酸中毒、非糖尿病酮症酸中毒性疾病、特殊病毒感染、药物中毒、特殊人群、难治性癫痫等疾病的发生预测、预后存在相关性,是许多疾病发生的预测因素或某些生理因素情况下的病理状态。虽然酮体不是特异性指标,但酮体的检测简单便捷、费用低、可重复性强,便于临床医生对疾病做出相应处理与治疗,降低并发症及死亡率,提高治愈率。Ketone bodies are the metabolic intermediates of human fat by liver, and participate in the energy supply of human. But excessive amounts of them lead to acidosis, causing the disorder of acid-base balance. Previous studies have found that ketone bodies are related to the incidence and prognosis of some diseases such as diabetic ketoacidosis, non-diabetic ketoacidosis diseases, specific viral infections, drug poisoning, special populations, intractable epilepsy. It is a strong predictor of certain diseases or pathological conditions in the presence of certain physiological factors. Ketone bodies are not specific indexes, but the detection of ketone bodies is simple and convenient, with low cost and high repeatability. Therefore, it is convenient for clinical doctors to make decisions and treatment according to the results, and then to reduce complications and mortality, but to improve the cure rate.

关 键 词：尿酮体 病理状态 生理状态 尿酮体阳性利与弊 合理诊断 

分 类 号：R5[医药卫生—内科学]