糖尿病行为学异常及STZ糖尿病小鼠模型  

Behavioral Abnormalities of Diabetes Mellitus and Streptozotocin-Induced Diabetic Mouse Model

作　　者：高逸龙 袁玲玲[2] 

机构地区：[1]郑州大学医学院2018级临床6班,河南 郑州 [2]河北医科大学第二医院内分泌科,河北 石家庄

出　　处：《临床医学进展》2020年第7期1348-1352,共5页Advances in Clinical Medicine

摘　　要：糖尿病发病率及病死率逐年升高,糖尿病患者可表现出行为学异常,行为学异常包括行为异常和心理异常,无论是行为异常还是心理异常均降低了糖尿病患者的生活质量、提高了医疗成本,早期识别糖尿病行为学异常可帮助患者提高生活质量、降低医疗成本。糖尿病动物模型主要包括1型糖尿病模型及2型糖尿病模型等,其中诱发性1型糖尿病模型中的链脲佐菌素诱导的糖尿病小鼠模型应用最为广泛。Diabetes Mellitus and related morbidity and mortality are increasing at an alarming rate, and diabetic patients can show abnormalities, they include behavioral abnormalities and psychological abnormalities. Both behavioral and psychological abnormalities can reduce the quality of life of diabetic patients and increase medical costs. Early identification of diabetic abnormalities can help patients improve their quality of life and reduce medical costs. Diabetic animal models mainly include type 1 and type 2, among which streptozotocin-induced diabetic mouse model is the most widely used.

关 键 词：糖尿病 行为 模型 链脲佐菌素 

分 类 号：R58[医药卫生—内分泌]