脂代谢异常的糖尿病患者的中医证型与炎症细胞因子的相关性研究  

Relationship between TCM Syndrome Type and Inflammatory Cytokines in Diabetic Patients with Abnormal Lipid Metabolism

作　　者：张黎洋 唐红[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海

出　　处：《临床医学进展》2020年第9期1971-1978,共8页Advances in Clinical Medicine

摘　　要：近些年来,脂代谢异常的糖尿病患者的发病率正在迅速的增长,到2030年,全球患病人口将达到5.51亿。2001年Mc Garry提出:显著脂代谢异常为2型糖尿病及其并发症的原发性病理生理过程,并建议将糖尿病改称为“糖脂病”。且多项证据表明:糖、脂代谢异常是一种“慢性低度炎症状态”,炎症细胞因子中的肿瘤坏死因子(TNF)、白介素(IL)等,在脂代谢异常合并糖尿病发病机制中起着重要的中介作用。目前治疗脂质代谢异常合并糖尿病的西药虽多,副反应也不可忽视。相比较之下,中医药治疗虽然起效慢,疗程长,但其优势在于不仅能控制血脂、血糖,防治糖尿病的并发症及伴随症状,毒副作用小,提高生活质量,而且能调整体质,达到治未病的目的。现对脂代谢异常的糖尿病患者的中医证型与炎症细胞因子的相关性研究概况予以综述。In recent years, the incidence of diabetes with abnormal lipid metabolism is increasing rapidly. By 2030, the number of people affected will reach 551 million. And in 2001, Mc Garry proposed that the significant abnormal lipid metabolism is the primary pathophysiological process of type 2 diabetes and its complications, and suggested that diabetes be renamed “glycolithiasis”. And a number of evidences show that: sugar and fat metabolism abnormalities are a “chronic low inflammation state”. Tumor necrosis factor (TNF), interleukin (IL), adiponectin, etc. in inflammatory cytokines play an important intermediary role in the pathogenesis of abnormal lipid metabolism and diabetes. At present, there are many Western drugs for treating abnormal lipid metabolism and diabetes, and the side effects cannot be ignored. In contrast, although the treatment of traditional Chinese medicine is slow and long, its advantages lie in not only the control of blood fat, blood sugar, prevention and treatment of complications and accompanying symptoms of diabetes, less toxic and side effects, improve the quality of life, but also can adjust the constitution, achieve the cure. In this paper, the TCM syndrome types, inflammatory cells and cytokines in diabetic patients with abnormal Lipid metabolism are reviewed.

关 键 词：脂代谢异常 2型糖尿病 炎症细胞因子 中医 综述 

分 类 号：R58[医药卫生—内分泌]