高原环境下血栓形成机制的研究进展  

Research Progress on Thrombosis Mechanism in High Altitude Environment

作　　者：费雪莲 王卓亚[2] 

机构地区：[1]青海大学,青海 西宁 [2]青海大学附属医院,青海 西宁

出　　处：《临床医学进展》2021年第5期2361-2367,共7页Advances in Clinical Medicine

摘　　要：环境对人体的生命健康有着至关重要的影响,是人类赖以生存和发展的物质基础条件。每年因各种原因进入高原的人数逐年增多,已有研究表明高原深静脉血栓的发生率较平原明显为高,可能与低氧所致血液高凝状态有关。因此,高原环境被认为是血栓形成的额外风险因素,但高原环境下血栓形成机制相当复杂,近年来,有许多针对高原环境下血栓形成机制的研究。本综述旨在提供一个全面系统的分析总结,以期待对后期临床工作及后续研究提供指导性意见。The environment has a crucial impact on the life and health of the human body and is the material basis for the survival and development of mankind. The annual number of people entering the plateau due to various reasons is increasing year by year, and studies have shown that the incidence of deep venous thrombosis at high altitude is significantly higher than that in the plain, which may be related to the hypercoagulable state of blood caused by hypoxia. Therefore, high altitude environment is considered as an additional risk factor for thrombosis, but the mechanism of thrombosis in high altitude environment is quite complex, and in recent years, there have been many studies on the mechanism of thrombosis in high altitude environment. The purpose of this review is to provide a comprehensive and systematic summary of the analysis in anticipation of guiding later clinical work and subsequent research.

关 键 词：高原 缺氧 血小板活化 血栓形成 

分 类 号：R54[医药卫生—心血管疾病]