光化性痒疹1例  

Actinic Prurigo: A Case Report

作　　者：陈忠业 王丽金 徐羽健 

机构地区：[1]广州中医药大学金沙洲医院皮肤科,广东 广州

出　　处：《临床医学进展》2021年第9期3870-3875,共6页Advances in Clinical Medicine

摘　　要：报道1例光化性痒疹。患儿女,6岁,面部、四肢丘疹,红斑、结血痂、伴瘙痒2年余。部分皮疹融合成肥厚性斑块或苔藓样变,各处皮损见散在凹陷性浅瘢痕。组织学示表皮角化过度伴部分角化不全,棘层轻度规则肥厚,基底层稍增厚,局灶性真皮浅层血管周围大量淋巴细胞浸润。诊断光化性痒疹。予沙利度胺等口服及外用糖皮质激素和他克莫司疗效良好。并回顾本病的流行病学、临床、病理、诊断及治疗,以提高临床医生对本病的认识。A case of actinic prurigo is report. A 6-year-old girl with itchy papules, erythema and hemorrhagic crusts on her face, limbs, back of hands and feet for more than 2 years. Some of the lesions coalesce to form hypertrophic or lichenified plaques, and small pitted scars were also presented. Skin biopsy revealed that hyperkeratosis with partial aceratosis of epidermis, mild regular acanthosis, thickening of the basal membrane, dense perivascular lymphocytic infiltrate in focal superficial dermis. A diagnosis of actinic prurigo was made, the treatments of oral thalidomide and topical corticosteroids and tacrolimus are effective. The epidemiology, clinical manifestation, pathology, diagnosis and treatment of actinic prurigo were reviewed to improve dermatologists’ understanding of the disease.

关 键 词：光化性痒疹 光敏性皮肤病 沙利度胺 

分 类 号：R75[医药卫生—皮肤病学与性病学]