有关痛风、载脂蛋白B以及心血管疾病的研究进展  

Research Progress on Gout, Apolipoprotein B and Cardiovascular Diseases

作　　者：李洁[1] 杨玉媛 李海铭 王忠超[1] 

机构地区：[1]青岛大学附属医院内分泌与代谢性疾病科,山东 青岛 [2]青岛大学附属医院老年医学科,山东 青岛

出　　处：《临床医学进展》2021年第9期4231-4235,共5页Advances in Clinical Medicine

摘　　要：痛风是内分泌常见的代谢紊乱性疾病之一,近些年来痛风的患病率逐年增加,而且易合并脂蛋白代谢异常,增加了痛风患者罹患心脑血管疾病的风险,不利于痛风患者的生活质量;同时脂蛋白代谢异常也是痛风发作及罹患心脑血管疾病的危险因素,三者之间相互关联。近来研究发现,痛风患者可伴有载脂蛋白B的异常,其在心血管疾病风险预测的作用优于低密度脂蛋白。现通过对文献收集整理,对痛风、载脂蛋白B以及心血管疾病的关系进行综述。Gout is one of the common endocrine metabolic disorders. In recent years, the prevalence of gout has increased year by year, and it is easy to be associated with abnormal lipoprotein metabolism, which increases the risk of gout in patients suffering from cardiovascular and cerebrovascular diseases, and is not conducive to the quality of life of gout patients. At the same time, abnormal lipoprotein metabolism is also a risk factor for gout attack and cardiovascular and cerebrovascular diseases, and the three are interrelated. Recent studies have found that patients with gout are associated with abnormal apolipoprotein B, which is better than LDL in predicting cardiovascular disease risk. This paper reviews the relationship between gout, apolipoprotein B and cardiovascular disease.

关 键 词：痛风 载脂蛋白B 心血管疾病 动脉粥样硬化 

分 类 号：R58[医药卫生—内分泌]