CTRP9与糖尿病视网膜病变关系的研究进展  

Research Progress of the Relationship between CTRP9 and Diabetic Retinopathy

作　　者：朱晓燕 刘勤 金涛[1] 白惠玲[2] 张书[2] 

机构地区：[1]甘肃中医药大学,第一临床医学院(甘肃省人民医院),甘肃 兰州 [2]甘肃省人民医院,眼科,甘肃 兰州

出　　处：《临床医学进展》2021年第11期4912-4918,共7页Advances in Clinical Medicine

摘　　要：糖尿病视网膜病变在糖尿病微血管病变中是最为主要的病变,也是其最严重的并发症之一,如果不能够及时治疗将可能导致终身失明,而糖尿病视网膜病变的发病机制比较复杂,目前尚未完全阐述清楚,主要由炎症、氧化应激和细胞凋亡引起。补体C1q肿瘤坏死因子相关蛋白9 (C1q/TNF-related protein 9, CTRP9)是最接近脂联素旁系同源物的脂肪细胞因子,以往的研究表明CTRP9主要在心血管疾病的研究中发挥着重要作用,近年来有研究发现它在糖尿病视网膜病变中也发挥有益的作用。本文就CTRP9与糖尿病视网膜病变关系的研究进展做一综述。Diabetic retinopathy is the most important lesion in diabetic microangiopaemia and one of its most serious complications. If not treated in time, it may lead to lifelong blindness. However, the pathogenesis of diabetic retinopathy is complicated and has not been fully explained yet. It is mainly caused by inflammation, oxidative stress and apoptosis. C1q/TNF-related protein 9 (CTRP9) is the adipocytokine closest to the adiponectin parafunctional homolog. Previous studies have shown that CTRP9 mainly plays an important role in the study of cardiovascular diseases. In recent years, it has been found that it also plays a beneficial role in diabetic retinopathy. This article reviews the research progress of the relationship between CTRP9 and diabetic retinopathy.

关 键 词：CTRP9 脂联素 糖尿病视网膜病变 

分 类 号：R58[医药卫生—内分泌]