获得性维生素K依赖性凝血因子缺乏症诊治进展  

Progress in the Diagnosis and Treatment of Acquired Vitamin K-Dependent Coagulation Factor Deficiency

作　　者：杨文舒 李永萍 

机构地区：[1]大理大学第一附属医院血液科,云南 大理

出　　处：《临床医学进展》2022年第5期3755-3761,共7页Advances in Clinical Medicine

摘　　要：在临床工作中,相当一部分出血性疾病由获得性维生素K依赖性凝血因子缺乏症(acquired deficiency of vitamin K-dependent clotting factors, ADVKCF)所致,其可能原因包括维生素K (vitamin K)的合成障碍、吸收减少及维生素K拮抗剂的过量摄入等。常见的临床表现为各个部位不同程度的出血,该病在治疗过程中由于维生素K种类及剂量的选择不同可能造成该病不同的治疗效果,本文将就此进行综述。A significant proportion of bleeding disorders in clinical work are caused by acquired deficiency of vitamin K-dependent clotting factors (ADVKCF), which may be caused by disorders of vitamin K synthesis, decreased absorption, and excessive intake of vitamin K antagonists. Common clinical manifestations are different degrees of bleeding in various parts, and the disease may have different therapeutic effects due to different types and doses of vitamin K during treatment, and this article will review this article.

关 键 词：获得性维生素K依赖性凝血因子缺乏症 维生素K 凝血因子 维生素K拮抗剂 

分 类 号：R977.26[医药卫生—药品]