粪便Hp抗原检测对UBT假阴性患者的诊断意义  

Diagnostic Value of Stool Antigen Test for the Detection of Hp Infection in UBT False-Negatives

作　　者：张庆龙 郑旭[3] 王莉莉[1] 李志鹏 董全江[1] 

机构地区：[1]青岛大学医学院附属青岛市市立医院中心实验室,山东 青岛 [2]山东第一医科大学(山东省医学科学院),山东 济南 [3]青岛大学医学院附属青岛市市立医院检验科,山东 青岛

出　　处：《临床医学进展》2022年第8期7071-7077,共7页Advances in Clinical Medicine

摘　　要：在诊断幽门螺杆菌(Hp)感染的非侵入性检测中,尿素呼气试验(UBT)具有很高的敏感性与特异性,是最常用的检测方法,但在临床中易受到多种因素干扰从而影响检测效果。近年来,粪便抗原检测(HpSA)以其较高的敏感性与特异性以及较低的成本成为诊断Hp感染的常用检测方法,本文将评价尿素呼气试验易出现假阴性的患者中实行粪便抗原检测的可靠性以及其诊断意义。Among the non-invasive tests for the diagnosis of Helicobacter pylori (Hp) infection, the urea breath test (UBT) has high sensitivity and specificity and is the most commonly used test, but it is suscep-tible to interference by various factors in the clinical setting, thus affecting the effectiveness of the test. In recent years, Hp stool antigen test (HpSA) has become a common test for the diagnosis of Hp infection due to its high sensitivity and specificity and low cost. In this paper, we will evaluate the reliability and diagnostic value of stool antigen test in patients with false negative urea breath test.

关 键 词：幽门螺杆菌 尿素呼气试验 粪便抗原检测 质子泵抑制剂 慢性萎缩性胃炎 

分 类 号：R446.6[医药卫生—诊断学]