青年女性患者冠脉严重病变影响因素的研究进展  

Research Progress on Risk Factors for Severe Coronary Artery Disease in Young Female Patients

作　　者：赵丽 魏子秀[2] 

机构地区：[1]山东第一医科大学(山东省医学科学院)临床医学院,山东 济宁 [2]济宁医学院附属济宁市第一人民医院,山东 济宁

出　　处：《临床医学进展》2022年第8期7983-7991,共9页Advances in Clinical Medicine

摘　　要：随着生活方式的改变,心血管疾病危险因素暴露增加,青年女性人群中冠心病的发病率及病死率逐年上升。本文旨在探讨45岁以下女性严重冠脉病变患者的危险因素研究进展,包括传统危险因素血脂异常、糖尿病、冠心病家族史、二手烟,以及新型高危因素如高同型半胱氨酸、高尿酸、低胆红素、一些炎症因子等。为规避及降低青年女性罹患严重冠脉病变的风险,需对高危人群进行早期筛查,对已产生冠脉严重病变的患者及时干预,对改善预后有重要意义。With the change of lifestyle and the increased exposure to cardiovascular disease risk factors, the incidence and mortality of coronary heart disease (CHD) in young women have increased year by year. The purpose of this study was to explore the research progress of risk factors for severe coro-nary heart disease in women under 45 years old, including the traditional risk factors such as dyslipidemia, diabetes, family history of CHD, second-hand smoke, and the new risk factors such as high homocysteine, high uric acid, high fibrinogen, and inflammatory cytokines. In order to avoid and reduce the risk of severe coronary heart disease in young women, early screening should be carried out in high-risk groups, and timely intervention should be conducted in patients with se-vere coronary artery disease.

关 键 词：青年女性 冠心病 肥胖 糖尿病 血脂异常 低胆红素 高同型半胱氨酸 高尿酸 

分 类 号：R541.4[医药卫生—心血管疾病]