有机磷农药中毒的研究进展  

Research Progress of Organophosphorus Poisoning

作　　者：伊职职 冯传杰[2] 

机构地区：[1]延安大学,陕西 延安 [2]延安大学附属医院急诊内科,陕西 延安

出　　处：《临床医学进展》2022年第9期8305-8310,共6页Advances in Clinical Medicine

摘　　要：口服有机磷农药后需彻底洗胃,必要时需多次灌肠排出毒物;中毒后会出现烟碱样(N)及毒蕈碱样(M)症状,患者会出现腺体分泌增加及肌束震颤等症状,给予阿托品可拮抗M、N样症状;复能剂可解救尚未老化的胆碱酯酶;血液灌流可清除已入血的毒物;血液透析可清除已入血毒物产生的炎症因子;脂肪乳可将有机磷从血浆中置换出来;如出现呼吸衰竭,则需早期使用呼吸机辅助呼吸;有部分患者可能会出现相关并发症,需进一步治疗。After oral administration of organophosphorus pesticides, gastric lavage should be done thorough-ly, and enema should be repeated to discharge the poison if necessary. After poisoning, nicotinoid and muscarinic symptoms will appear, and patients will have symptoms such as increased glandu-lar secretion and muscle bundle tremor. Administration of atropine can antagonize M and N symp-toms. The reactivator can rescue the cholinesterase before aging;Hemoperfusion removes toxins that have entered the blood;Hemodialysis can remove inflammatory factors produced by toxins in the blood;Fat emulsion can replace organophosphorus from plasma;In case of respiratory failure, early use of ventilator to assist breathing;Some patients may have related complications and need further treatment.

关 键 词：综述 有机磷中毒 

分 类 号：R595.4[医药卫生—内科学]