非侵袭性真菌性鼻窦炎的研究进展  

Research Progress of Non-Invasive Fungal Sinusitis

作　　者：王柯柯 张英[1] 

机构地区：[1]青海大学附属医院耳鼻咽喉科学,青海 西宁

出　　处：《临床医学进展》2023年第2期1426-1433,共8页Advances in Clinical Medicine

摘　　要：非侵袭性真菌性鼻窦炎多由于鼻窦被霉菌感染所引起的病理性免疫炎症反应。传统观点认为,非侵袭性霉菌性鼻窦炎(Non-invasive fungal rhinosinusitis, NIFS)的发生多与抗生素的广泛使用、环境污染,免疫抑制剂及抗肿瘤药物或放疗等相关,也可以在机体抵御侵袭能力下降的某一局部致病时发生。但近年来发现,在健康体检中亦可发现真菌性鼻窦炎,造成这种情况的原因尚不清楚,有待进一步研究。由于鼻窦炎的发病因素较为复杂,免疫性因素、组织病理反应、诊断及治疗等各有其特点,现就NIFS的免疫学特性、组织病理学特征、影像学诊断及治疗方法的研究进展作一综述。Non invasive fungal sinusitis is usually caused by pathological immune inflammation caused by fungal infection of the sinuses. According to the traditional view, the occurrence of non-invasive fungal rhinosinusitis (NIFS) is mostly related to the widespread use of antibiotics, environmental pollution, immunosuppressants, anti-tumor drugs or radiotherapy, and can also occur when the body’s ability to resist invasion decreases in a certain part of the disease. However, in recent years, it has been found that fungal sinusitis can also be found in the physical examination of healthy indi-viduals. The cause of this situation is still unclear and needs further research. Because the patho-genic factors of nasosinusitis are complex, and the immune factors, histopathological reactions, di-agnosis and treatment have their own characteristics, this article reviews the research progress of the immunological characteristics, histopathological characteristics, imaging diagnosis and treat-ment methods of NIFS.

关 键 词：非侵袭性真菌性鼻窦炎 免疫学特性 组织病理学特征 诊断 治疗 综述 

分 类 号：R76[医药卫生—耳鼻咽喉科]