儿童热性惊厥发病机制相关研究进展  

Advances in Research Related to the Pathogenesis of Febrile Convulsions in Chil-dren

作　　者：代琛 贾鲲鹏[1] 

机构地区：[1]延安大学附属医院儿科,陕西 延安

出　　处：《临床医学进展》2023年第3期3731-3735,共5页Advances in Clinical Medicine

摘　　要：惊厥是一种严重危害儿童身体健康甚至危及生命安全的危急重症,尽管对于儿童时期来说惊厥绝大多数预后是比较好的,但仍有部分呈反复发作,甚至会导致成人期的癫痫发作及认知功能障碍等神经系统后遗症。惊厥的发作机制及病因复杂,儿童反复发生惊厥可能对神经系统遗留不同程度的后遗症,甚至发展为癫痫,因此成为目前国内外研究热点。惊厥从发病至一次病情痊愈的过程中,给患儿、家庭及社会造成很大负担。随着医学科学研究的不断进步,惊厥越来越引起学者们的关注,并较多地对病因、危险因素、发病机制、预测惊厥复发指标及预后方面的规律进行了研究,使临床医师对该类疾病的诊治有了更多认识,现对儿童时期发生惊厥的发病机制与血清学指标的改变相关研究进展作一综述。Convulsion is a critical illness that seriously endangers children’s health and even life safety. Alt-hough the vast majority of convulsions in children have a good prognosis, some still have recurrent seizures, and even lead to neurological sequelae such as seizures and cognitive impairment in adults. The seizure mechanism and etiology of convulsion are complex, repeated convulsions in children may leave different degrees of sequelae on the nervous system, and even develop into epi-lepsy, which makes it a research hotspot at home and abroad. Convulsions cause a great burden to children, families and society in the process from onset to recovery. With the continuous progress of medical scientific research, convulsion has attracted more and more attention of scholars, and more studies have been carried out on the etiology, risk factors, pathogenesis, prediction of convulsion recurrence indicators and prognosis, so that clinicians have more understanding of the diagnosis and treatment of this kind of disease. Now this paper summarizes the relevant research progress and changes of serological indexes of convulsion in childhood.

关 键 词：儿童惊厥 发病机制 热性惊厥 良性惊厥 中枢神经系统感染 

分 类 号：R72[医药卫生—儿科]