右美托咪定在分娩镇痛中的研究进展  

Research Progress of Dexmedetomidine in Analgesia during Labor

作　　者：杨小波 雷升霞 罗志锴[1] 

机构地区：[1]延安大学附属医院麻醉科,陕西 延安 [2]榆林市第二医院麻醉科,陕西 榆林

出　　处：《临床医学进展》2023年第4期5138-5145,共8页Advances in Clinical Medicine

摘　　要：近年来,随着国家生育政策的放开,越来越多产妇会面临分娩方式抉择。自然分娩的疼痛,确实会让不少女性继续选择剖宫产,因此,为了减少剖宫产率,确切可靠的优质分娩镇痛效果显得尤为重要。右美托咪定(Dexmedetomidine, DEX)具有镇静镇痛、抗寒颤、抗谵妄、抗焦虑、抗抑郁、减少麻醉药用量、轻度呼吸抑制等诸多优势,其安全性和有效性,以及能够给患者提供一定程度的舒适度,使其成为一种重要的硬膜外分娩镇痛麻醉佐剂,广泛应用于临床。本文就其药理学特性、对机体的影响以及在分娩镇痛领域的应用进展进行综述,旨在为分娩镇痛用药提供参考和依据。In recent years, with the opening of the national fertility policy, more and more women will face the choice of childbirth mode. The pain of natural childbirth will indeed make many women continue to choose cesarean section;therefore, in order to reduce the rate of cesarean section, the exact and re-liable high-quality analgesic effect of childbirth is particularly important. Dexmedetomidine (DEX) has the advantages of sedation and analgesia, anti-shivering, anti-delirium, anti-anxiety, an-ti-depression, reduced narcotic dosage, mild respiratory depression, etc. Its safety and efficacy, as well as its ability to provide patients with a certain degree of comfort, make it as an important an-esthetic adjuvant widely used for epidural labor pain relief. This article reviews its pharmacological properties, effects on the body and its application in the field of labor analgesia, in order to provide reference and basis for labor analgesia.

关 键 词：右美托咪定 分娩镇痛 产后抑郁 临床研究 

分 类 号：R61[医药卫生—外科学]