儿童流感嗜血杆菌流行病学及感染变化  

Epidemiology and Infection Changes of Haemophilus Influenzae in Children

作　　者：郑文婷 李渠北[1] 

机构地区：[1]重庆医科大学附属儿童医院呼吸中心,儿科学重庆市重点实验室,儿童发育疾病研究教育部重点实验室,国家儿童健康与疾病临床医学研究中心,重庆

出　　处：《临床医学进展》2023年第4期5406-5412,共7页Advances in Clinical Medicine

摘　　要：流感嗜血杆菌是一种儿童感染常见病原菌,在开展疫苗接种之前,b型流感嗜血杆菌(Hib)是脑膜炎、儿童肺炎的重要病原体,随着Hib疫苗在各地区覆盖率的增高,流感嗜血杆菌的流行病学已经发生了变化,以无荚膜不可分型流感嗜血杆菌(NTHi)为主,并且由于流感嗜血杆菌的抗生素耐药性逐步增加,对儿童仍是较重疾病负担。本文对儿童流感嗜血杆菌的相关研究进行综述,总结其流行病学、感染现状及治疗的进展。Haemophilus influenzae (Hi) is a common pathogen of infection in children. Before vaccination, Haemophilus influenzae, especially Haemophilus influenzae type b (Hib), was an important cause of bacterial meningitis and pneumonia in children. With the increase of Hib vaccine coverage in vari-ous regions, the epidemiology of Haemophilus influenzae has changed, and now the nontypeable H. influenzae (NTHi) becomes the main strain. Additionally, due to the increasing of antibiotic re-sistance, H. influenzae is still a heavy disease burden for children. This article will review the epi-demiology of Haemophilus influenza, current infection status and treatment of H. influenzae in chil-dren.

关 键 词：儿童 流感嗜血杆菌 流行病学 疫苗接种 综述 

分 类 号：R44[医药卫生—诊断学]