重叠综合征研究进展  

Advances in Research of Overlap Syndrome

作　　者：孙文娟 杨发满[1] 李晓平[1] 

机构地区：[1]青海大学附属医院老年医学科,青海 西宁

出　　处：《临床医学进展》2023年第5期8621-8626,共6页Advances in Clinical Medicine

摘　　要：研究发现睡眠呼吸暂停综合征、慢性阻塞性肺疾病与炎症因子、维生素存在相关性,然而,关于OS患者维生素D状态及炎症因子的证据很少。近期研究发现睡眠呼吸暂停综合征导致的慢性间歇性缺氧、高碳酸血症、炎症因子释放、交感神经激活等机制与慢性阻塞性肺疾病的不可逆性气道阻塞有一定的共通性。本文就机制进一步阐述维生素D状态及炎症因子在其两种疾病中的共同特点。Studies have found that sleep apnea syndrome and chronic obstructive pulmonary disease are as-sociated with inflammatory factors and vitamins. However, there is little evidence on vitamin D status and inflammatory factors in patients with OS. Recent studies have found that the mecha-nisms of chronic intermittent hypoxia, hypercapnia, inflammatory cytokine release, and sympa-thetic nerve activation caused by sleep apnea syndrome have certain commonness with irreversible airway obstruction in chronic obstructive pulmonary disease. This article further elucidates the mechanism of vitamin D status and the common characteristics of inflammatory cytokines in both diseases.

关 键 词：重叠综合征 慢性阻塞性肺疾病 阻塞性睡眠呼吸暂停综合征 炎症因子 维生素D 研究进展 综述 

分 类 号：R47[医药卫生—护理学]