慢性乙型病毒性肝炎不同治疗方式的临床研究概况  

Clinical Survey of Different Treatment Methods for Chronic Viral Hepatitis B

作　　者：厉绾 李萍英 

机构地区：[1]青海大学研究生院,青海 西宁 [2]青海省人民医院消化内科,青海 西宁

出　　处：《临床医学进展》2023年第7期11108-11112,共5页Advances in Clinical Medicine

摘　　要：慢性乙型肝炎是世界范围内的主要公共卫生问题,病程呈进行性发展,可发展至肝硬化、肝癌甚至死亡。对于此类患者,早期治疗非常重要,治疗的主要目标是通过长期抑制病毒复制、缓解肝坏死炎症和纤维化,从而降低肝细胞癌发生的风险来提高生存率和生活质量。目前基于WHO提出的2030年消除乙型肝炎的目标,慢性乙型肝炎的治疗方式成为探索的热点。本文综述了慢性乙型病毒性肝炎不同治疗方式的临床研究概况。Chronic hepatitis B is a major public health problem worldwide. The course of the disease is pro-gressive, including cirrhosis, liver cancer and even death. Early treatment is important for these patients. The main goal of treatment is to improve survival and quality of life by reducing the risk of hepatocellular carcinoma by long-term inhibition of viral replication, relief of necrosis inflammation and fibrosis of the liver. At present, based on the goal proposed by WHO to eliminate hepatitis B in 2030, the treatment of chronic hepatitis B has become a hot topic of exploration. This article re-views the clinical research of different treatment methods for chronic viral hepatitis B.

关 键 词：慢性乙型病毒性肝炎 聚乙二醇化干扰素 核苷(酸)类似物 药物治疗 

分 类 号：R51[医药卫生—内科学]