心外膜脂肪组织及其与房颤关系的研究进展  

Research Progress on Epicardial Adipose Tissue and Its Relationship with Atrial Fibrillation

作　　者：杨雪松 李展[2] 张玉娇[2] 任满意[2] 侯应龙 

机构地区：[1]山东大学齐鲁医学院,山东 济南 [2]山东第一医科大学第一附属医院(山东省千佛山医院)心内科,山东 济南

出　　处：《临床医学进展》2023年第7期11410-11415,共6页Advances in Clinical Medicine

摘　　要：心外膜脂肪组织(EAT)是位于心肌与心包脏层之间的代谢活跃的脂肪库。相比于人体其他内脏脂肪库,EAT不仅具有产热、机械保护的共同特性,还兼有独特分泌功能。研究证实,EAT与房颤的发生及射频消融术后复发相关。EAT导致房颤的机制尚未完全阐明,可能的机制涉及心肌纤维化、脂肪细胞浸润、神经调节失衡等。近年来,EAT受到高度关注,或许会成为预测房颤发生及房颤射频术后复发的一项危险因素。Epicardial adipose tissue (EAT) is an active metabolic fat reservoir located between the myocardi-um and the visceral layer of the pericardium. Compared to other visceral fat reservoirs in the hu-man body, EAT not only has common characteristics of heat production and mechanical protection, but also has unique secretion functions. Research has confirmed that EAT is associated with the oc-currence of atrial fibrillation and recurrence after radiofrequency ablation. The mechanism of EAT leading to atrial fibrillation has not been fully clarified, and the possible mechanism involves myo-cardial fibrosis, adipocyte infiltration, neuromodulation imbalance, etc. In recent years, EAT has received high attention and may become a risk factor for predicting the occurrence and recurrence of atrial fibrillation after radiofrequency surgery.

关 键 词：房颤 心外膜脂肪组织 射频消融 

分 类 号：R54[医药卫生—心血管疾病]