脓毒症急性肾损伤生物标记物进展  

Progression of Biomarkers of Acute Kidney Injury in Sepsis

作　　者：郭思帅 郭峻氚[2] 

机构地区：[1]新疆医科大学研究生院,新疆 乌鲁木齐 [2]新疆维吾尔自治区人民医院重症医学科,新疆 乌鲁木齐

出　　处：《临床医学进展》2023年第10期15621-15626,共6页Advances in Clinical Medicine

摘　　要：脓毒症是一种复杂的临床综合征,其特征是对感染性损伤的全身炎症反应。这一过程往往导致广泛的组织损伤和多器官功能障碍。特别是急性肾损伤(acute kidney injury, AKI)的发生是最常见的并发症之一,它增加了治疗的复杂性和费用,是死亡的一个独立危险因素。脓毒症引起的AKI的高死亡率令人无法接受,部分原因是对其诊断延误。这篇综述的目的是关注脓毒症引起的AKI的相关的潜在诊断和预后标志物。Sepsis is a complex clinical syndrome characterized by a systemic inflammatory response to infec-tious injury. This process often leads to extensive tissue damage and multi-organ dysfunction. In particular, the occurrence of acute kidney injury (AKI) is one of the most common complications, which increases the complexity and cost of treatment and is an independent risk factor for death. The high mortality rate of AKI due to sepsis is unacceptable, in part due to delays in its diagnosis. The aim of this review was to focus on potential diagnostic and prognostic markers related to AKI due to sepsis.

关 键 词：脓毒症 脓毒症急性肾损伤 生物标志物 

分 类 号：R69[医药卫生—泌尿科学]