间充质干细胞在骨折愈合中的研究进展  

Research Progress of Mesenchymal Stem Cells in Fracture Healing

作　　者：刘虎 房好林[2,3] 

机构地区：[1]济宁医学院临床医学院,山东 济宁 [2]济宁市第一人民医院急诊创伤外科,山东 济宁 [3]济宁市医学科学研究院创伤研究所,山东 济宁

出　　处：《临床医学进展》2023年第10期16301-16307,共7页Advances in Clinical Medicine

摘　　要：骨折的临床治疗目的是在最短的时间内获得尽可能好的功能恢复,骨折延迟愈合或不愈合是一个常见的骨折并发症,大约10%的骨折病例中,可能出现骨折延迟愈合或不愈合。这不仅给患者带来巨大的痛苦,还给患者家庭带来一定的经济负担,同时耗费大量的社会医疗资源。如何减轻骨折病人的痛苦,加速骨折的愈合,对患者的快速康复具有重要意义。随着骨折愈合的深入研究,发现间充质干细胞在骨折愈合中发挥至关重要的作用。因此,本文综述了间充质干细胞概念、发展历程,经处理的间充质干细胞在骨折修复中的作用与功能。The purpose of clinical treatment of fracture is to obtain the best possible functional recovery in the shortest time. Delayed or non-union fracture is a common complication of fracture, and delayed or non-union fracture may occur in about 10% of fracture cases. This not only brings great pain to pa-tients, but also brings a certain economic burden to patients’ families, and consumes a lot of social medical resources. How to reduce the pain of fracture patients and accelerate the healing of fracture is of great significance to the rapid recovery of patients. With the further study of fracture healing, it is found that mesenchymal stem cells play a vital role in fracture healing. Therefore, this article re-viewed the concept and development of mesenchymal stem cells, and the role and function of treated mesenchymal stem cells in fracture repair.

关 键 词：间充质干细胞 骨折愈合 处理措施 

分 类 号：R68[医药卫生—骨科学]