脉冲振荡肺功能在成人支气管哮喘诊疗中的研究进展  

Research Progress of Impulse Oscillatory Lung Function in the Diagnosis and Treatment of Adult Bronchial Asthma

作　　者：玛力亚·牙生 尼尔佳玛丽·木塔力甫 克丽别娜·吐尔逊[1] 

机构地区：[1]新疆医科大学第一附属医院呼吸中心,新疆 乌鲁木齐

出　　处：《临床医学进展》2023年第11期18001-18006,共6页Advances in Clinical Medicine

摘　　要：我国支气管哮喘的患病率呈现快速上升的趋势,支气管哮喘已成为我国患病率最高的慢性气道疾病之一。根据临床实践结果分析,若哮喘早期得到规范化的诊断,获得行之有效的治疗,这对哮喘患者良好的预后有重要的意义。因此关于诊断哮喘方法的研究层出不穷。在过去的几十年中,脉冲振荡法(Impulse oscillometry, IOS)在肺功能测试中取得了进展。振荡测量法也被用于临床和研究方面。关于其在支气管哮喘、慢性阻塞性肺疾病、间质性肺病、小气道疾病、囊性纤维化、阻塞性睡眠呼吸暂停综合征和其他病症中的作用已经被证实。多年来,许多研究证明了IOS在诊断和监测哮喘患者中的重要性,其最大的优点是能够监测疾病的进程和以简单的方式评估治疗效果,即,对患者配合的要求最低,测量快速且可重复。此外,如果患者不能执行依赖于强迫呼吸,IOS是特别有用的。尽管有其优点,但该技术在世界各地的官方推荐中仍然很少。尽管如此,对于IOS的研究层出不穷,它可能很快与标准肺功能测试相提并论。这篇综述的目的是总结IOS在支气管哮喘中的研究进展。The prevalence of bronchial asthma in China shows a rapidly increasing trend and bronchial asthma has become one of the chronic airway diseases with the highest prevalence in China. According to the analysis of the results of clinical practice, early standardized diagnosis and effective treatment is important for the good prognosis. Therefore, research on methods of diagnosing asthma is prolif-erating. In the past decades, impulse oscillometry (IOS) has made progress in pulmonary function testing. Oscillometry has also been used in clinical and research settings. Regarding its role in bronchial asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD), small airway disease (SAD), cystic fibrosis (CF), obstructive sleep apnea syndrome (OSAS) and other conditions have been demonstrated. Over the years, many studies have demonstrated the im-portance of IOS in the diagnosis and monitoring of patients with asthma, with the greatest ad-vantage being the ability to monitor the course of the disease and to assess the effectiveness of the treatment in a simple way, i.e., with minimal requirements for patient cooperation, and with meas-urements that are rapid and reproducible. In addition, the IOS is particularly useful if the patient is unable to perform dependent on forced breathing. Despite its advantages, the technique remains scarce in official recommendations worldwide. Nonetheless, there is a proliferation of studies on the IOS, and it may soon be compared with standard pulmonary function tests. The aim of this review is to summarize the progress of research on IOS in bronchial asthma.

关 键 词：肺功能 脉冲振荡 支气管哮喘 呼吸阻力 呼吸阻抗 

分 类 号：R56[医药卫生—呼吸系统]