不同药物预防丙泊酚静脉注射痛的机制及研究进展  

Mechanism and Research Progress of Different Drugs in Preventing Intravenous Propofol Injection Pain

作　　者：赖鹏冲 尹光芬 

机构地区：[1]大理大学临床医学院,云南 大理 [2]大理大学第一附属医院麻醉科,云南 大理

出　　处：《临床医学进展》2023年第12期18947-18953,共7页Advances in Clinical Medicine

摘　　要：虽然丙泊酚是目前临床麻醉日常工作中使用最广泛的镇静药物,但每当给患者静脉注射丙泊酚时所带来的注射痛仍然是一个不可忽略的重大问题。随着社会发展与医学进步,现代医学对丙泊酚静脉注射痛的发生机制已有很多研究,能够有效地预防或减轻丙泊酚静脉注射痛的各种策略与药物日益俱增。本文旨在对能够预防丙泊酚静脉注射痛的一些常用药物及其预防机制还有相关研究进展做归纳总结。Although propofol is the most widely used sedative drug in the daily work of clinical anesthesia at present, the injection pain caused by intravenous injection of propofol is still a major problem that cannot be ignored. With the development of society and medical progress, there have been many researches on the mechanism of pain caused by intravenous propofol injection in modern medicine, and various strategies and drugs that can effectively prevent or alleviate pain caused by intrave-nous propofol injection are increasing day by day. The purpose of this article is to summarize some commonly used drugs to prevent pain from intravenous propofol injection and their prevention mechanisms as well as related research progress.

关 键 词：丙泊酚 注射痛 预防药物 预防机制 研究进展 

分 类 号：R61[医药卫生—外科学]